Primus Anabolics

Quickstart – Highlights

GHK-Cu (glycyl-L-histidyl-L-lysine-copper complex) is a naturally occurring copper peptide with documented functions in wound healing, tissue remodeling, and skin regeneration.

Research demonstrates activity in gene regulation related to collagen synthesis, antioxidant defense, and anti-inflammatory pathways. This educational protocol presents practical subcutaneous administration approaches based on clinical practice patterns.

Reconstitution: Add 3.0 mL of sterile water → 16.67 mg/mL concentration.
Typical range: 1.0–2.0 mg per injection (most common protocols use 5 days per week or 3 times per week).
Easy measurement: At 16.67 mg/mL, 1 unit = 0.01 mL ≈ 167 mcg on a U-100 insulin syringe.
Storage: Lyophilized: store at −20 °C (−4 °F) or below; reconstituted: refrigerate at 2–8 °C (35.6–46.4 °F) and use within 30 days.

50 mg GHK-Cu Vial
Dosage and Reconstitution Guide
Educational guide for reconstitution and common dosage patterns
Standard / conservative approach (3 mL = 16.67 mg/mL; 5 days per week)

Weeks 1–4

Dose per injection: 1.0 mg (1000 mcg) Units: 6 units (0.06 mL)

Weeks 5–8

Dose: 1.5 mg (1500 mcg) Units: 9 units (0.09 mL)

Weeks 9–12+

Dose: 2.0 mg (2000 mcg) Units: 12 units (0.12 mL) Frequency: Inject once daily, 5 days per week subcutaneously. This gradual titration allows evaluation of individual tolerance while maintaining practical injection volumes. For administrations of 10 units or less (0.10 mL or less), consider 30 or 50-unit syringes for better visual precision.

Reconstitution Steps

Draw 3.0 mL of sterile or bacteriostatic water with a sterile syringe.
Inject slowly down the side of the vial to minimize foaming.
Gently swirl until the peptide is completely dissolved (do not shake vigorously).
Label with reconstitution date and refrigerate at 2–8 °C, protected from light.

Alternative Protocol (3 mL = 16.67 mg/mL; 3 times per week)

Weeks 1–12+

Dose per injection: 2.0 mg (2000 mcg) Units: 12 units (0.12 mL) Frequency: Inject 2 mg three times per week (e.g., Monday/Wednesday/Friday). This protocol maintains consistent weekly dosing (~6 mg per week) with fewer injections. Important: This guide is for educational purposes only and does not constitute medical advice. For research use only. Not for human consumption.

Required Supplies

Plan based on an 8–16 week protocol. GHK-Cu peptide vials, 50 mg each, PRICE €13 per 50mg vial 5 days per week (1.0–2.0 mg a day): 8 weeks (~50 mg total) ≈ 1 vial 12 weeks (~90 mg total) ≈ 2 viales (Wait, viales -> vials) 16 weeks (~130 mg total) ≈ 3 vials 3 times per week (2 mg each time): 8 weeks (~48 mg) ≈ 1 vial 12 weeks (~72 mg) ≈ 2 vials 16 weeks (~96 mg) ≈ 2 vials Sterile or bacteriostatic water (10 mL bottles): Use approximately 3.0 mL per vial. 1 vial protocols: 3 mL → 1 bottle of 10 mL 2 vials: 6 mL → 1 bottle 3 viales: 9 mL → 1 bottle (Wait, viales -> vials)

Protocol Summary

Objective: Support tissue remodeling, wound healing, and skin regeneration through documented biological pathways. Duration: 8–12 weeks (extensible to 16 if desired). Dose: 1.0–2.0 mg per injection; frequency of 3–5 days per week. Reconstitution: 3.0 mL per 50 mg vial (16.67 mg/mL). Storage: Lyophilized frozen; reconstituted refrigerated and use within 30 days.

How It Works

GHK-Cu is a natural tripeptide that forms complexes with copper ions to modulate multiple biological processes. It has been shown to be involved in healing by increasing collagen and decorin gene expression, activating tissue remodeling pathways, and regulating genes associated with antioxidant defense and anti-inflammatory response. Preclinical studies show activity at very low doses in animal models, while in clinical practice, milligram-range doses are used for systemic effects. The peptide exhibits multifunctional activity in skin, nervous system, and vascular tissue, with regulatory effects beyond simple healing.

Potential Benefits and Observed Effects

Supports healing and tissue repair through collagen synthesis and remodeling.
Positive regulatory effects on genes related to antioxidant enzymes, growth factors, and anti-inflammatory signaling.
Activity observed in nervous system function in preclinical models.
Generally well tolerated; common side effects are mild injection site reactions.
No official human dosing guidelines exist; not FDA approved.

Injection Technique

Clean vial stopper and injection site with alcohol and let dry completely.
Pinch a skin fold and insert the needle at a 45–90° angle into the subcutaneous tissue.
Do not aspirate in subcutaneous injections; inject slowly and steadily.
Remove the needle at the same insertion angle; press gently if necessary.
Rotate injection sites systematically to avoid local irritation.
Dispose of used syringes in a suitable sharps container.

GHK-CU